Assay Detail
Binding
CHEMBL894051
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Plasmodium falciparum LDH
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.00 | 5.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL242020 | — | — | 1 | 5.76 |
| CHEMBL51483 | GOSSYPOL | 3.0 | 1 | 5.58 |
| CHEMBL242019 | — | — | 1 | 5.50 |
| CHEMBL390488 | — | — | 1 | 5.08 |
| CHEMBL245025 | — | — | 1 | 4.06 |
| CHEMBL15976 | OXAMATE | — | 1 | 4.03 |
| CHEMBL390487 | — | — | 1 | - |
| CHEMBL245247 | — | — | 1 | - |
| CHEMBL245248 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL242020 | — | IC50 | = | 1750.0 | nM | 5.76 |
| CHEMBL51483 | GOSSYPOL | IC50 | = | 2640.0 | nM | 5.58 |
| CHEMBL242019 | — | IC50 | = | 3130.0 | nM | 5.50 |
| CHEMBL390488 | — | IC50 | = | 8250.0 | nM | 5.08 |
| CHEMBL245025 | — | IC50 | = | 87300.0 | nM | 4.06 |
| CHEMBL15976 | OXAMATE | IC50 | = | 92500.0 | nM | 4.03 |
| CHEMBL390487 | — | IC50 | = | 191000.0 | nM | - |
| CHEMBL245247 | — | IC50 | > | 241000.0 | nM | - |
| CHEMBL245248 | — | IC50 | - | — | - |