Assay Detail
Binding
CHEMBL894934
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Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescent assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Orally bioavailable potent soluble epoxide hydrolase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.17 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL242655 | — | — | 1 | 8.52 |
| CHEMBL242459 | — | — | 1 | 8.10 |
| CHEMBL436774 | AR9281 | 2.0 | 1 | 8.05 |
| CHEMBL215387 | — | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL242655 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL242459 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL436774 | AR9281 | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL215387 | — | IC50 | = | 10.0 | nM | 8.00 |