Assay Detail
Functional
CHEMBL896017
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Growth inhibition of human A375 cells after 3 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A-375 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Doxazolidine induction of apoptosis by a topoisomerase II independent mechanism.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.85 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL217089 | DOXAZOLIDINE | — | 1 | 9.00 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL217089 | DOXAZOLIDINE | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 199.53 | nM | 6.70 |