Assay Detail
Binding
CHEMBL896165
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Binding affinity to AR
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Synthesis and characterization of nonsteroidal glucocorticoid receptor modulators for multiple myeloma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.41 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL397920 | — | — | 1 | 6.96 |
| CHEMBL395716 | — | — | 1 | 6.82 |
| CHEMBL394369 | — | — | 1 | 6.54 |
| CHEMBL397919 | — | — | 1 | 6.54 |
| CHEMBL428922 | — | — | 1 | 6.46 |
| CHEMBL244537 | — | — | 1 | 5.82 |
| CHEMBL243656 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL397920 | — | Ki | = | 110.0 | nM | 6.96 |
| CHEMBL395716 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL394369 | — | Ki | = | 290.0 | nM | 6.54 |
| CHEMBL397919 | — | Ki | = | 290.0 | nM | 6.54 |
| CHEMBL428922 | — | Ki | = | 346.0 | nM | 6.46 |
| CHEMBL244537 | — | Ki | = | 1530.0 | nM | 5.82 |
| CHEMBL243656 | — | Ki | = | 1900.0 | nM | 5.72 |