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Assay Detail

CHEMBL896782

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of factor 10a
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Coagulation factor X (CHEMBL244)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Aminopyrrolidineamide inhibitors of site-1 protease.
Hay BA, Abrams B, Zumbrunn AY, Valentine JJ, Warren LC, Petras SF, Shelly LD, Xia A, Varghese AH, Hawkins JL, Van Camp JA, Robbins MD, Landschulz K, Harwood HJ.
Bioorg Med Chem Lett (2007) 17 : 4411 -4414
PubMed 17583500 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.00 4.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL233611 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL233611 IC50 = 100000.0 nM 4.00