Assay Detail
Functional
CHEMBL896887
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human A375 cells by MTS assay after 24 hrs
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A-375 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.76 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL244711 | — | — | 1 | 6.05 |
| CHEMBL244712 | — | — | 1 | 5.92 |
| CHEMBL244901 | — | — | 1 | 5.91 |
| CHEMBL396549 | — | — | 1 | 5.90 |
| CHEMBL244900 | — | — | 1 | 5.78 |
| CHEMBL244322 | — | — | 1 | 5.70 |
| CHEMBL428921 | — | — | 1 | 5.62 |
| CHEMBL244899 | — | — | 1 | 5.60 |
| CHEMBL395485 | — | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL244711 | — | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL244712 | — | IC50 | = | 1190.0 | nM | 5.92 |
| CHEMBL244901 | — | IC50 | = | 1220.0 | nM | 5.91 |
| CHEMBL396549 | — | IC50 | = | 1250.0 | nM | 5.90 |
| CHEMBL244900 | — | IC50 | = | 1680.0 | nM | 5.78 |
| CHEMBL244322 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL428921 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL244899 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL395485 | — | IC50 | = | 4660.0 | nM | 5.33 |