Assay Detail
Binding
CHEMBL898305
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Inhibition of human leukocyte antigen related protein-tyrosine phosphatase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Receptor-type tyrosine-protein phosphatase F (CHEMBL3521) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
5-Arylidene-2,4-thiazolidinediones as inhibitors of protein tyrosine phosphatases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.59 | 4.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL393606 | — | — | 1 | 4.61 |
| CHEMBL235595 | — | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL393606 | — | IC50 | = | 24600.0 | nM | 4.61 |
| CHEMBL235595 | — | IC50 | = | 27000.0 | nM | 4.57 |