Assay Detail
Binding
CHEMBL898604
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Displacement of [3H]17beta-estradiol from recombinant human ERbeta
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Aza analogues of equol: novel ligands for estrogen receptor beta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.57 | 8.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44 | GENISTEIN | 2.0 | 1 | 8.17 |
| CHEMBL239938 | — | — | 1 | 7.08 |
| CHEMBL391619 | — | — | 1 | 6.85 |
| CHEMBL239723 | — | — | 1 | 6.66 |
| CHEMBL392029 | — | — | 1 | 6.64 |
| CHEMBL240157 | — | — | 1 | 6.28 |
| CHEMBL240369 | — | — | 1 | 5.53 |
| CHEMBL240160 | — | — | 1 | 5.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44 | GENISTEIN | IC50 | = | 6.8 | nM | 8.17 |
| CHEMBL239938 | — | IC50 | = | 83.0 | nM | 7.08 |
| CHEMBL391619 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL239723 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL392029 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL240157 | — | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL240369 | — | IC50 | = | 2950.0 | nM | 5.53 |
| CHEMBL240160 | — | IC50 | = | 4900.0 | nM | 5.31 |