Assay Detail
Functional
CHEMBL898606
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human ERalpha expressed in yeast AH109 by yeast two hybrid assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Aza analogues of equol: novel ligands for estrogen receptor beta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.17 | 6.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44 | GENISTEIN | 2.0 | 1 | 6.09 |
| CHEMBL239723 | — | — | 1 | 4.82 |
| CHEMBL239938 | — | — | 1 | 4.61 |
| CHEMBL396309 | — | — | 1 | - |
| CHEMBL240370 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44 | GENISTEIN | EC50 | = | 810.0 | nM | 6.09 |
| CHEMBL239723 | — | EC50 | = | 15200.0 | nM | 4.82 |
| CHEMBL239938 | — | EC50 | = | 24330.0 | nM | 4.61 |
| CHEMBL396309 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL240370 | — | EC50 | > | 100000.0 | nM | - |