Assay Detail
Binding
CHEMBL899646
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Binding affinity at human adrenergic beta-1 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.67 | 9.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL500 | PINDOLOL | 4.0 | 1 | 9.28 |
| CHEMBL393648 | — | — | 1 | 8.62 |
| CHEMBL236514 | — | — | 1 | 8.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL500 | PINDOLOL | Ki | = | 0.52 | nM | 9.28 |
| CHEMBL393648 | — | Ki | = | 2.37 | nM | 8.62 |
| CHEMBL236514 | — | Ki | = | 7.92 | nM | 8.10 |