Assay Detail
Binding
CHEMBL900202
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]niacin from mouse GPR109A
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.60 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL573 | NIACIN | 4.0 | 1 | 6.85 |
| CHEMBL391813 | — | — | 1 | 6.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL573 | NIACIN | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL391813 | — | IC50 | = | 460.0 | nM | 6.34 |