Assay Detail
Functional
CHEMBL900986
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mouse delta-opioid receptor by MVD assay
10
Total Activities
10
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Development of novel enkephalin analogues that have enhanced opioid activities at both mu and delta opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.06 | 8.74 |
| Activity | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL235109 | — | — | 1 | 8.74 |
| CHEMBL392207 | — | — | 1 | 7.62 |
| CHEMBL235743 | — | — | 1 | 6.92 |
| CHEMBL439026 | — | — | 1 | 6.60 |
| CHEMBL235107 | — | — | 1 | 6.60 |
| CHEMBL392206 | — | — | 1 | 6.54 |
| CHEMBL235106 | — | — | 1 | 6.42 |
| CHEMBL216239 | CARBOXYFENTANYL | — | 1 | - |
| CHEMBL392185 | — | — | 1 | - |
| CHEMBL235108 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL235109 | — | IC50 | = | 1.8 | nM | 8.74 |
| CHEMBL392207 | — | IC50 | = | 24.0 | nM | 7.62 |
| CHEMBL235743 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL439026 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL235107 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL392206 | — | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL235106 | — | IC50 | = | 380.0 | nM | 6.42 |
| CHEMBL216239 | CARBOXYFENTANYL | Activity | = | 1.0 | % | - |
| CHEMBL392185 | — | Activity | = | 10.0 | % | - |
| CHEMBL235108 | — | Activity | = | 3.0 | % | - |