Assay Detail
Binding
CHEMBL901488
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Inhibition of Escherichia coli methionine aminopeptidase in presence of 100 uM Manganese
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibition of monometalated methionine aminopeptidase: inhibitor discovery and crystallographic analysis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.61 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200238 | — | — | 1 | 6.29 |
| CHEMBL238659 | — | — | 1 | 5.37 |
| CHEMBL200849 | — | — | 1 | 5.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200238 | — | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL238659 | — | IC50 | = | 4310.0 | nM | 5.37 |
| CHEMBL200849 | — | IC50 | = | 6560.0 | nM | 5.18 |