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Assay Detail

CHEMBL901582

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of horse liver alcohol dehydrogenase
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Equus caballus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues.
Chen L, Gao G, Felczak K, Bonnac L, Patterson SE, Wilson D, Bennett EM, Jayaram HN, Hedstrom L, Pankiewicz KW.
J Med Chem (2007) 50 : 5743 -5751
PubMed 17958343 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 11 4.41 4.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL429702 1 4.41
CHEMBL265870 1 -
CHEMBL414564 1 -
CHEMBL394277 1 -
CHEMBL264107 1 -
CHEMBL409560 1 -
CHEMBL392204 1 -
CHEMBL410745 1 -
CHEMBL392203 1 -
CHEMBL235533 1 -
CHEMBL441190 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL429702 IC50 = 39000.0 nM 4.41
CHEMBL265870 IC50 - -
CHEMBL414564 IC50 - -
CHEMBL394277 IC50 - -
CHEMBL264107 IC50 - -
CHEMBL409560 IC50 > 50000.0 nM -
CHEMBL392204 IC50 > 50000.0 nM -
CHEMBL410745 IC50 > 50000.0 nM -
CHEMBL392203 IC50 > 50000.0 nM -
CHEMBL235533 IC50 > 50000.0 nM -
CHEMBL441190 IC50 > 50000.0 nM -