Assay Detail
Binding
CHEMBL901622
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Displacement of [3H]CP-55940 from CB1 receptor in rat brain synaptosomes
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Synaptosomes |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 7.69 | 9.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL109393 | — | — | 1 | 9.02 |
| CHEMBL238359 | — | — | 1 | 8.59 |
| CHEMBL235585 | — | — | 1 | 8.27 |
| CHEMBL113230 | — | — | 1 | 7.41 |
| CHEMBL266712 | — | — | 1 | 6.44 |
| CHEMBL429797 | — | — | 1 | 6.40 |
| CHEMBL188 | WIN-552122 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL109393 | — | Ki | = | 0.95 | nM | 9.02 |
| CHEMBL238359 | — | Ki | = | 2.6 | nM | 8.59 |
| CHEMBL235585 | — | Ki | = | 5.4 | nM | 8.27 |
| CHEMBL113230 | — | Ki | = | 39.0 | nM | 7.41 |
| CHEMBL266712 | — | Ki | = | 360.0 | nM | 6.44 |
| CHEMBL429797 | — | Ki | = | 400.0 | nM | 6.40 |
| CHEMBL188 | WIN-552122 | Ki | - | — | - |