Assay Detail
Binding
CHEMBL901623
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]CP-55940 from CB2 receptor in mouse spleen membranes
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Tissue | Spleen |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 8.55 | 9.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL429797 | — | — | 1 | 9.09 |
| CHEMBL109393 | — | — | 1 | 8.96 |
| CHEMBL113230 | — | — | 1 | 8.51 |
| CHEMBL238359 | — | — | 1 | 8.32 |
| CHEMBL235585 | — | — | 1 | 8.23 |
| CHEMBL266712 | — | — | 1 | 8.17 |
| CHEMBL188 | WIN-552122 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL429797 | — | Ki | = | 0.82 | nM | 9.09 |
| CHEMBL109393 | — | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL113230 | — | Ki | = | 3.1 | nM | 8.51 |
| CHEMBL238359 | — | Ki | = | 4.8 | nM | 8.32 |
| CHEMBL235585 | — | Ki | = | 5.9 | nM | 8.23 |
| CHEMBL266712 | — | Ki | = | 6.7 | nM | 8.17 |
| CHEMBL188 | WIN-552122 | Ki | - | — | - |