Assay Detail
Binding
CHEMBL901749
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat uPA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Urokinase-type plasminogen activator (CHEMBL1075245) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Small, potent, and selective diaryl phosphonate inhibitors for urokinase-type plasminogen activator with in vivo antimetastatic properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.66 | 7.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL393591 | — | — | 1 | 7.71 |
| CHEMBL393979 | — | — | 1 | 7.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL393591 | — | IC50 | = | 19.5 | nM | 7.71 |
| CHEMBL393979 | — | IC50 | = | 24.5 | nM | 7.61 |