Assay Detail
Functional
CHEMBL903469
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Cytotoxicity against mouse P19 cells after 18 hrs
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P19 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Geldanamycin derivatives and neuroprotective effect on cultured P19-derived neurons.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.75 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278315 | GELDANAMYCIN | 2.0 | 1 | 7.00 |
| CHEMBL397319 | — | — | 1 | 7.00 |
| CHEMBL391544 | — | — | 1 | 6.70 |
| CHEMBL443488 | — | — | 1 | 6.30 |
| CHEMBL391545 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278315 | GELDANAMYCIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL397319 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL391544 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL443488 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL391545 | — | IC50 | > | 10000.0 | nM | - |