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Assay Detail

CHEMBL906378

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human ACC1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Acetyl-CoA carboxylase 1 (CHEMBL3351)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors.
Li JJ, Wang H, Tino JA, Robl JA, Herpin TF, Lawrence RM, Biller S, Jamil H, Ponticiello R, Chen L, Chu CH, Flynn N, Cheng D, Zhao R, Chen B, Schnur D, Obermeier MT, Sasseville V, Padmanabha R, Pike K, Harrity T.
Bioorg Med Chem Lett (2007) 17 : 3208 -3211
PubMed 17383874 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.22 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL399379 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL399379 IC50 = 6000.0 nM 5.22