Assay Detail
Functional
CHEMBL906753
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Singlet oxygen scavenging activity by assessed as inhibition of DHR oxidation
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.12 | 5.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL228623 | — | — | 1 | 5.31 |
| CHEMBL1430 | PENICILLAMINE | 4.0 | 1 | 5.31 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.28 |
| CHEMBL228622 | — | — | 1 | 5.19 |
| CHEMBL374372 | — | — | 1 | 5.10 |
| CHEMBL374371 | — | — | 1 | 5.00 |
| CHEMBL151 | LUTEOLIN | 2.0 | 1 | 4.63 |
| CHEMBL390582 | — | — | 1 | - |
| CHEMBL228673 | — | — | 1 | - |
| CHEMBL415858 | — | — | 1 | - |
| CHEMBL228625 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL228623 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL1430 | PENICILLAMINE | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL50 | QUERCETIN | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL228622 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL374372 | — | IC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL374371 | — | IC50 | = | 10100.0 | nM | 5.00 |
| CHEMBL151 | LUTEOLIN | IC50 | = | 23400.0 | nM | 4.63 |
| CHEMBL390582 | — | IC50 | = | 265800.0 | nM | - |
| CHEMBL228673 | — | IC50 | = | 182800.0 | nM | - |
| CHEMBL415858 | — | IC50 | = | 162600.0 | nM | - |
| CHEMBL228625 | — | IC50 | = | 245000.0 | nM | - |