Assay Detail
Functional
CHEMBL906759
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Nitric oxide scavenging activity assessed as inhibition of DAF2 oxidation
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.85 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL228623 | — | — | 1 | 6.62 |
| CHEMBL374371 | — | — | 1 | 6.54 |
| CHEMBL374372 | — | — | 1 | 6.47 |
| CHEMBL228622 | — | — | 1 | 6.29 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.71 |
| CHEMBL151 | LUTEOLIN | 2.0 | 1 | 5.58 |
| CHEMBL226335 | RUTIN | 3.0 | 1 | 5.44 |
| CHEMBL415858 | — | — | 1 | 4.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL228623 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL374371 | — | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL374372 | — | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL228622 | — | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL50 | QUERCETIN | IC50 | = | 1950.0 | nM | 5.71 |
| CHEMBL151 | LUTEOLIN | IC50 | = | 2610.0 | nM | 5.58 |
| CHEMBL226335 | RUTIN | IC50 | = | 3660.0 | nM | 5.44 |
| CHEMBL415858 | — | IC50 | = | 73900.0 | nM | 4.13 |