Assay Detail
Binding
CHEMBL907143
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Binding affinity to 5HT1A receptor
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Arylmethyloxyphenyl derivatives: small molecules displaying P-glycoprotein inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL216198 | — | — | 1 | 5.30 |
| CHEMBL217886 | — | — | 1 | 5.30 |
| CHEMBL384538 | — | — | 1 | 5.30 |
| CHEMBL214739 | — | — | 1 | 5.30 |
| CHEMBL215010 | — | — | 1 | 5.30 |
| CHEMBL217281 | — | — | 1 | 5.30 |
| CHEMBL217425 | — | — | 1 | 5.30 |
| CHEMBL387052 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL216198 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL217886 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL384538 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL214739 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL215010 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL217281 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL217425 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL387052 | — | Ki | = | 5000.0 | nM | 5.30 |