Assay Detail
Binding
CHEMBL907467
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Inhibition of human factor 2a after 10 seconds
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.90 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL245678 | — | — | 2 | 5.58 |
| CHEMBL391804 | — | — | 1 | 4.57 |
| CHEMBL391805 | — | — | 1 | 4.54 |
| CHEMBL393873 | — | — | 1 | 4.44 |
| CHEMBL247732 | — | — | 1 | - |
| CHEMBL439391 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL245678 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL245678 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL391804 | — | IC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL391805 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL393873 | — | IC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL247732 | — | IC50 | > | 100.0 | nM | - |
| CHEMBL439391 | — | IC50 | > | 100000.0 | nM | - |