Assay Detail
Functional
CHEMBL907688
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of L-type calcium channel by FLIPR assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Voltage-gated L-type calcium channel (CHEMBL2095229) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
Discovery and synthesis of tetrahydroindolone-derived carbamates as Kv1.5 blockers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.70 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL216281 | — | — | 1 | 4.70 |
| CHEMBL217347 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL216281 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL217347 | — | IC50 | > | 30000.0 | nM | - |