Assay Detail
Functional
CHEMBL908904
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of SREBP1c expression in Huh7 cell line
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Discovery of phenyl acetic acid substituted quinolines as novel liver X receptor agonists for the treatment of atherosclerosis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.59 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL217118 | — | — | 1 | 7.82 |
| CHEMBL214719 | — | — | 1 | 7.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL217118 | — | EC50 | = | 15.0 | nM | 7.82 |
| CHEMBL214719 | — | EC50 | = | 45.0 | nM | 7.35 |