Assay Detail
Functional
CHEMBL909461
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Antiviral activity against HIV1 3B assessed as reduction in cytopathic effect in MT4 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Configurationally restricted bismacrocyclic CXCR4 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.56 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2311028 | PLERIXAFOR OCTAHYDROCHLORIDE | — | 1 | 7.96 |
| CHEMBL213871 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2311028 | PLERIXAFOR OCTAHYDROCHLORIDE | EC50 | = | 11.0 | nM | 7.96 |
| CHEMBL213871 | — | EC50 | = | 6980.0 | nM | 5.16 |