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Assay Detail

CHEMBL910318

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of non-phosphorylated form of rabbit muscle glycogen phosphorylase in presence of glycogen and 45 mM phosphate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Glycogen phosphorylase, muscle form (CHEMBL4696)
Type SINGLE PROTEIN
Organism Oryctolagus cuniculus

Publication

Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
Oikonomakos NG, Tiraidis C, Leonidas DD, Zographos SE, Kristiansen M, Jessen CU, Nørskov-Lauritsen L, Agius L.
J Med Chem (2006) 49 : 5687 -5701
PubMed 16970395 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.47 6.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL215137 1 6.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL215137 Ki = 342.0 nM 6.47