Assay Detail
Functional
CHEMBL910469
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Antibacterial activity against Escherichia coli K12 by broth microdilution method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.57 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL203125 | FOSMIDOMYCIN | 3.0 | 1 | 6.66 |
| CHEMBL56073 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL203125 | FOSMIDOMYCIN | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL56073 | — | IC50 | = | 33000.0 | nM | 4.48 |