Assay Detail
Functional
CHEMBL910710
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at human NK3 receptor expressed in CHO cells assessed as increase in inositol phosphate generation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.35 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL106124 | SENKTIDE | — | 1 | 8.52 |
| CHEMBL373569 | ELEDOISIN | 2.0 | 1 | 8.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL106124 | SENKTIDE | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL373569 | ELEDOISIN | EC50 | = | 6.6 | nM | 8.18 |