Assay Detail
ADMET
CHEMBL912265
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Cytotoxicity against murine 3T3 cells by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An efficient and stereoselective dearylation of asarinin and sesamin tetrahydrofurofuran lignans to acuminatolide by methyltrioxorhenium/H(2)O(2) and UHP systems.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.11 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL43469 | ASARININ | — | 1 | 6.70 |
| CHEMBL220017 | — | — | 1 | 5.52 |
| CHEMBL414381 | — | — | 1 | - |
| CHEMBL387124 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL43469 | ASARININ | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL220017 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL414381 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL387124 | — | IC50 | > | 20000.0 | nM | - |