Assay Detail
Functional
CHEMBL912663
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at rat mGluR6 receptor measured as intracellular calcium concentration in HEK293 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Metabotropic glutamate receptor 6 (CHEMBL3842) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Design and synthesis of APTCs (aminopyrrolidinetricarboxylic acids): identification of a new group III metabotropic glutamate receptor selective agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.74 | 4.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285043 | — | — | 1 | 4.74 |
| CHEMBL212233 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285043 | — | EC50 | = | 18400.0 | nM | 4.74 |
| CHEMBL212233 | — | EC50 | = | 378000.0 | nM | - |