Assay Detail
Binding
CHEMBL913151
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Inhibition of human placental DPP4 at pH 2
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Synthesis and characterization of constrained peptidomimetic dipeptidyl peptidase IV inhibitors: amino-lactam boroalanines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.17 | 9.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL63860 | — | — | 1 | 9.27 |
| CHEMBL67279 | TALABOSTAT | 3.0 | 1 | 8.80 |
| CHEMBL2068511 | — | — | 1 | 8.28 |
| CHEMBL2068512 | — | — | 1 | 6.32 |
| CHEMBL305170 | — | — | 1 | 5.64 |
| CHEMBL196120 | — | — | 1 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL63860 | — | IC50 | = | 0.54 | nM | 9.27 |
| CHEMBL67279 | TALABOSTAT | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL2068511 | — | IC50 | = | 5.3 | nM | 8.28 |
| CHEMBL2068512 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL305170 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL196120 | — | IC50 | = | 21000.0 | nM | 4.68 |