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Assay Detail

CHEMBL914264

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]PK 11195 from PBR in Sprague-Dawley rat cerebral cortex
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Cerebral cortex
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Translocator protein (CHEMBL4552)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor.
Margiotta N, Ostuni R, Ranaldo R, Denora N, Laquintana V, Trapani G, Liso G, Natile G.
J Med Chem (2007) 50 : 1019 -1027
PubMed 17286392 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.55 8.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL220661 1 8.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL220661 IC50 = 2.81 nM 8.55