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Assay Detail

CHEMBL915534

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of TNFalpha production in LPS-stimulated human primary monocytes by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Monocyte
Confidence 1 — Organism
Curated By Autocuration

Target

Monocyte (CHEMBL614076)
Type CELL-LINE
Organism Homo sapiens

Publication

Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-Pyrone from Helichrysum italicum ssp. microphyllum.
Appendino G, Ottino M, Marquez N, Bianchi F, Giana A, Ballero M, Sterner O, Fiebich BL, Munoz E.
J Nat Prod (2007) 70 : 608 -612
PubMed 17315926 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.04 5.04

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL225421 ARZANOL 1 5.04

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL225421 ARZANOL IC50 = 9200.0 nM 5.04