Assay Detail
ADMET
CHEMBL916479
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Cytotoxicity against human U87-Mg cells after 72 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | U-87MG ATCC |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Triterpenoid pyrazines and benzopyrazines with cytotoxic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.43 | 4.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222760 | — | — | 1 | 4.72 |
| CHEMBL153117 | — | — | 1 | 4.13 |
| CHEMBL431525 | BETUNOLIC ACID | — | 1 | - |
| CHEMBL222586 | — | — | 1 | - |
| CHEMBL376864 | — | — | 1 | - |
| CHEMBL222652 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222760 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL153117 | — | IC50 | = | 74000.0 | nM | 4.13 |
| CHEMBL431525 | BETUNOLIC ACID | IC50 | = | 159000.0 | nM | - |
| CHEMBL222586 | — | IC50 | = | 231000.0 | nM | - |
| CHEMBL376864 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL222652 | — | IC50 | = | 148000.0 | nM | - |