Assay Detail
ADMET
CHEMBL916481
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Cytotoxicity against daunorubicin-resistant CEM-DNR-bulk cells after 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Triterpenoid pyrazines and benzopyrazines with cytotoxic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.10 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL153117 | — | — | 1 | 5.30 |
| CHEMBL222760 | — | — | 1 | 4.89 |
| CHEMBL222586 | — | — | 1 | - |
| CHEMBL222652 | — | — | 1 | - |
| CHEMBL376864 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL153117 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL222760 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL222586 | — | IC50 | = | 235000.0 | nM | - |
| CHEMBL222652 | — | IC50 | = | 198000.0 | nM | - |
| CHEMBL376864 | — | IC50 | = | 250000.0 | nM | - |