Assay Detail
Functional
CHEMBL916805
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of IL5 production in conA and anti-CD3 antibody sensitized BALB/c mouse spleen T lymphocytes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Spleen |
| Cell Type | T-cell |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel 2-(substituted phenyl)benzimidazole derivatives with potent activity against IgE, cytokines, and CD23 for the treatment of allergy and asthma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.52 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222659 | — | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222659 | — | IC50 | = | 30.0 | nM | 7.52 |