Assay Detail
Functional
CHEMBL917002
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Antiprotozoal activity against Giardia intestinalis IMSS:0696:1 trophozoites after 48 hrs
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Giardia intestinalis |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antigiardial activity of triterpenoids from root bark of Hippocratea excelsa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.41 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL54804 | PRISTIMERIN | — | 1 | 6.96 |
| CHEMBL432519 | TINGENONE | — | 1 | 6.13 |
| CHEMBL137 | METRONIDAZOLE | 4.0 | 1 | 5.91 |
| CHEMBL267684 | XUXARINE EBETA | — | 1 | 4.95 |
| CHEMBL227442 | — | — | 1 | 4.70 |
| CHEMBL389695 | DZUNUNCANONE | — | 1 | 4.65 |
| CHEMBL390961 | — | — | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL54804 | PRISTIMERIN | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL432519 | TINGENONE | IC50 | = | 740.0 | nM | 6.13 |
| CHEMBL137 | METRONIDAZOLE | IC50 | = | 1230.0 | nM | 5.91 |
| CHEMBL267684 | XUXARINE EBETA | IC50 | = | 11300.0 | nM | 4.95 |
| CHEMBL227442 | — | IC50 | = | 19800.0 | nM | 4.70 |
| CHEMBL389695 | DZUNUNCANONE | IC50 | = | 22400.0 | nM | 4.65 |
| CHEMBL390961 | — | IC50 | = | 27400.0 | nM | 4.56 |