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Assay Detail

CHEMBL917185

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Functional
Agonistic activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically evoked twitch
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Tissue Vas deferens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Delta-type opioid receptor (CHEMBL3222)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Highly selective fluorescent analogue of the potent delta-opioid receptor antagonist Dmt-Tic.
Balboni G, Salvadori S, Dal Piaz A, Bortolotti F, Argazzi R, Negri L, Lattanzi R, Bryant SD, Jinsmaa Y, Lazarus LH.
J Med Chem (2004) 47 : 6541 -6546
PubMed 15588089 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.59 8.59

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2369958 1 8.59

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2369958 IC50 = 2.58 nM 8.59