Assay Detail
ADMET
CHEMBL919513
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Cytotoxicity against human SKBR3 cells after 96 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | SK-BR-3 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Gallium(III) and iron(III) complexes of alpha-N-heterocyclic thiosemicarbazones: synthesis, characterization, cytotoxicity, and interaction with ribonucleotide reductase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.58 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL221061 | — | — | 1 | 8.85 |
| CHEMBL374548 | — | — | 1 | 8.66 |
| CHEMBL223250 | — | — | 1 | 8.57 |
| CHEMBL373400 | — | — | 1 | 8.51 |
| CHEMBL221062 | — | — | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL221061 | — | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL374548 | — | IC50 | = | 2.2 | nM | 8.66 |
| CHEMBL223250 | — | IC50 | = | 2.7 | nM | 8.57 |
| CHEMBL373400 | — | IC50 | = | 3.1 | nM | 8.51 |
| CHEMBL221062 | — | IC50 | = | 5.0 | nM | 8.30 |