Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL920539

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effect on cell growth in dividing Swiss 3T3 cells by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type NIH3T3
Confidence 1 — Organism
Curated By Autocuration

Target

NIH3T3 (CHEMBL614822)
Type CELL-LINE
Organism Mus musculus

Publication

Identification of novel and improved antimitotic agents derived from noscapine.
Anderson JT, Ting AE, Boozer S, Brunden KR, Crumrine C, Danzig J, Dent T, Faga L, Harrington JJ, Hodnick WF, Murphy SM, Pawlowski G, Perry R, Raber A, Rundlett SE, Stricker-Krongrad A, Wang J, Bennani YL.
J Med Chem (2005) 48 : 7096 -7098
PubMed 16279766 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.41 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL376130 1 7.30
CHEMBL224797 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL376130 EC50 = 50.0 nM 7.30
CHEMBL224797 EC50 = 3000.0 nM 5.52