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Assay Detail

CHEMBL920954

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Functional
Inhibition of TNFalpha release in human whole blood
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Tissue Blood
Confidence 1 — Organism
Curated By Autocuration

Target

Blood (CHEMBL613416)
Type TISSUE
Organism Homo sapiens

Publication

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S.
Proc Natl Acad Sci U S A (2007) 104 : 20523 -20528
PubMed 18077363 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.44 5.44
Inhibition 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL111456 2 5.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL111456 IC50 = 3650.0 nM 5.44
CHEMBL111456 Inhibition = 3650.0 nM -