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Assay Detail

CHEMBL921247

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of LPS-induced TNFalpha production in mouse L929 cells after 4 hrs by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L929
Confidence 1 — Organism
Curated By Autocuration

Target

L929 (CHEMBL612267)
Type CELL-LINE
Organism Mus musculus

Publication

Anti-inflammatory activity profile of JANEX-1 in preclinical animal models.
Uckun FM, Tibbles H, Ozer Z, Qazi S, Vassilev A.
Bioorg Med Chem (2008) 16 : 1287 -1298
PubMed 18024136 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.84 4.84

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL405130 WHI-P131 1.0 1 4.84

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL405130 WHI-P131 IC50 = 14500.0 nM 4.84