Assay Detail
Binding
CHEMBL923744
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Inhibition of Renilla reniformis luciferase
45
Total Activities
45
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Renilla reniformis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Characterization of chemical libraries for luciferase inhibitory activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 28 | - | - |
| IC50 | 17 | 4.82 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL374632 | — | — | 1 | 5.28 |
| CHEMBL1200712 | EVANS BLUE | 4.0 | 1 | 5.00 |
| CHEMBL264933 | — | — | 1 | 4.96 |
| CHEMBL265715 | — | — | 1 | 4.96 |
| CHEMBL261118 | — | — | 1 | 4.96 |
| CHEMBL328710 | — | — | 1 | 4.72 |
| CHEMBL410484 | — | — | 1 | 4.70 |
| CHEMBL354261 | — | — | 1 | 4.70 |
| CHEMBL259615 | — | — | 1 | 4.65 |
| CHEMBL265686 | — | — | 1 | 4.60 |
| CHEMBL88553 | — | — | 1 | 4.44 |
| CHEMBL260560 | — | — | 1 | - |
| CHEMBL260342 | — | — | 1 | - |
| CHEMBL408850 | — | — | 1 | - |
| CHEMBL428789 | — | — | 1 | - |
| CHEMBL408563 | — | — | 1 | - |
| CHEMBL406368 | — | — | 1 | - |
| CHEMBL267160 | — | — | 1 | - |
| CHEMBL259460 | — | — | 1 | - |
| CHEMBL405914 | — | — | 1 | - |
| CHEMBL259784 | — | — | 1 | - |
| CHEMBL407501 | — | — | 1 | - |
| CHEMBL264931 | (R)-INDOPROFEN | — | 1 | - |
| CHEMBL406835 | — | — | 1 | - |
| CHEMBL35482 | — | — | 1 | - |
| CHEMBL198759 | — | — | 1 | - |
| CHEMBL66654 | — | — | 1 | - |
| CHEMBL88612 | — | — | 1 | - |
| CHEMBL408653 | — | — | 1 | - |
| CHEMBL473735 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL374632 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL1200712 | EVANS BLUE | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL264933 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL265715 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL261118 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL328710 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL410484 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL354261 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL259615 | — | IC50 | = | 22500.0 | nM | 4.65 |
| CHEMBL265686 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL88553 | — | IC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL260342 | — | Activity | - | — | - | |
| CHEMBL259103 | — | Activity | - | — | - | |
| CHEMBL260560 | — | Activity | - | — | - | |
| CHEMBL444376 | — | IC50 | - | — | - | |
| CHEMBL259421 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL411085 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL260213 | — | Activity | - | — | - | |
| CHEMBL258889 | — | Activity | - | — | - | |
| CHEMBL258888 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL260451 | — | Activity | - | — | - | |
| CHEMBL261123 | — | Activity | - | — | - | |
| CHEMBL405317 | — | Activity | - | — | - | |
| CHEMBL429335 | — | Activity | - | — | - | |
| CHEMBL406557 | — | Activity | - | — | - | |
| CHEMBL260028 | — | Activity | - | — | - | |
| CHEMBL259805 | — | Activity | - | — | - | |
| CHEMBL259422 | — | Activity | - | — | - | |
| CHEMBL407501 | — | Activity | - | — | - | |
| CHEMBL473735 | — | Activity | - | — | - | |
| CHEMBL408653 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL88612 | — | Activity | - | — | - | |
| CHEMBL66654 | — | Activity | - | — | - | |
| CHEMBL198759 | — | Activity | - | — | - | |
| CHEMBL35482 | — | Activity | - | — | - | |
| CHEMBL406835 | — | Activity | - | — | - | |
| CHEMBL264931 | (R)-INDOPROFEN | Activity | - | — | - | |
| CHEMBL408850 | — | Activity | - | — | - | |
| CHEMBL259784 | — | Activity | - | — | - | |
| CHEMBL405914 | — | Activity | - | — | - | |
| CHEMBL259460 | — | Activity | - | — | - | |
| CHEMBL267160 | — | Activity | - | — | - | |
| CHEMBL406368 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL408563 | — | Activity | - | — | - | |
| CHEMBL428789 | — | Activity | - | — | - |