Assay Detail
Binding
CHEMBL923887
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Inhibition of yeast alpha-glucosidase
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.57 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80254 | — | — | 1 | 6.75 |
| CHEMBL312653 | — | — | 1 | 5.96 |
| CHEMBL406973 | — | — | 1 | 5.00 |
| CHEMBL259905 | — | — | 1 | 4.55 |
| CHEMBL247666 | — | — | 1 | - |
| CHEMBL259721 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80254 | — | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL312653 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL406973 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL259905 | — | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL247666 | — | IC50 | = | 290000.0 | nM | - |
| CHEMBL259721 | — | IC50 | = | 900000.0 | nM | - |