Assay Detail
Functional
CHEMBL925062
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against human immunodeficiency virus 1 in cell culture
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Development of integrase inhibitors for treatment of AIDS: an overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC95 | 3 | - | - |
| EC50 | 2 | 7.44 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL204656 | ELVITEGRAVIR | 4.0 | 1 | 9.05 |
| CHEMBL49201 | — | — | 1 | 5.82 |
| CHEMBL50605 | — | — | 1 | - |
| CHEMBL403230 | — | — | 1 | - |
| CHEMBL414850 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL204656 | ELVITEGRAVIR | EC50 | = | 0.9 | nM | 9.05 |
| CHEMBL49201 | — | EC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL50605 | — | IC95 | = | 100.0 | nM | - |
| CHEMBL403230 | — | IC95 | = | 12000.0 | nM | - |
| CHEMBL414850 | — | IC95 | = | 100.0 | nM | - |