Assay Detail
Binding
CHEMBL925157
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat liver LDM
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Lanosterol 14-alpha demethylase (CHEMBL4981) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
The biology and chemistry of hyperlipidemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.22 | 6.22 |
| IC50 | 1 | 4.26 | 4.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL398686 | — | — | 1 | 6.22 |
| CHEMBL255059 | — | — | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL398686 | — | Ki | = | 600.0 | nM | 6.22 |
| CHEMBL255059 | — | IC50 | = | 55000.0 | nM | 4.26 |