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Assay Detail

CHEMBL925437

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Tobacco mosaic virus U1 after 72 hrs by half leaf method
8
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Tobacco mosaic virus
Confidence 1 — Organism
Curated By Intermediate

Target

Tobacco mosaic virus (CHEMBL613818)
Type ORGANISM
Organism Tobacco mosaic virus

Publication

Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase.
Wang YH, Zhang ZK, Yang FM, Sun QY, He HP, Di YT, Mu SZ, Lu Y, Chang Y, Zheng QT, Ding M, Dong JH, Hao XJ.
J Nat Prod (2007) 70 : 1458 -1461
PubMed 17822295 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Activity 6 - -
IC50 2 5.75 5.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL251056 1 5.75
CHEMBL252723 1 -
CHEMBL250055 1 -
CHEMBL465820 1 -
CHEMBL250866 1 -
CHEMBL400092 LYCORINE 1 -
CHEMBL1523 NORSANGUININE 1 -
CHEMBL1643 RIBAVIRIN 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL251056 IC50 = 1800.0 nM 5.75
CHEMBL252723 Activity - -
CHEMBL250055 Activity - -
CHEMBL465820 Activity - -
CHEMBL250866 Activity - -
CHEMBL400092 LYCORINE Activity - -
CHEMBL1523 NORSANGUININE Activity - -
CHEMBL1643 RIBAVIRIN IC50 = 2989600.0 nM -