Assay Detail
Functional
CHEMBL925546
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Cytotoxicity against human BCG823 cells after 48 hrs by sulforhodamine B assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BCG823 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cardenolides from Saussurea stella with cytotoxicity toward cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 7.14 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL399336 | CONVALLATOXIN | — | 1 | 7.80 |
| CHEMBL249081 | — | — | 1 | 7.80 |
| CHEMBL400878 | — | — | 1 | 7.25 |
| CHEMBL400356 | — | — | 1 | 7.16 |
| CHEMBL400877 | — | — | 1 | 7.11 |
| CHEMBL249260 | — | — | 1 | 7.00 |
| CHEMBL400876 | — | — | 1 | 6.92 |
| CHEMBL249248 | — | — | 1 | 6.64 |
| CHEMBL399334 | — | — | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL399336 | CONVALLATOXIN | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL249081 | — | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL400878 | — | IC50 | = | 56.0 | nM | 7.25 |
| CHEMBL400356 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL400877 | — | IC50 | = | 77.0 | nM | 7.11 |
| CHEMBL249260 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL400876 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL249248 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL399334 | — | IC50 | = | 290.0 | nM | 6.54 |