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Assay Detail

CHEMBL927522

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitumor activity against human Raji cells by trypan blue exclusion assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Raji
Confidence 1 — Organism
Curated By Autocuration

Target

Raji (CHEMBL614628)
Type CELL-LINE
Organism Homo sapiens

Publication

Design, synthesis, and biological evaluation of (E)-styrylbenzylsulfones as novel anticancer agents.
Reddy MV, Mallireddigari MR, Cosenza SC, Pallela VR, Iqbal NM, Robell KA, Kang AD, Reddy EP.
J Med Chem (2008) 51 : 86 -100
PubMed 18088089 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.23 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL253178 1 8.40
CHEMBL254849 1 8.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL253178 IC50 = 4.0 nM 8.40
CHEMBL254849 IC50 = 9.0 nM 8.05